Pubertal onset is controlled by complex neuronal networks in the brain. Remarkable progress has been made in our understanding of the neural regulation of puberty, however the exact timing mechanism of puberty and it’s modulation by stress remains to be fully elucidated. Traumatic stress can alter pubertal timing independent of adiposity. This is concerning as altered pubertal timing can have deleterious effects on the health of an individual later in life.

Stress and altered pubertal timing: Is the limbic brain the key?

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